Peritoneal Cancer

Laura Russell asked:


Mesothelioma is the growth of malignant cells in mesothelium, the thin membrane covering the body’s internal organs. This mesothelium lining covers the pleural, peritoneal and pericardial cavities. Pleura is a membrane covering the lungs and it is the most common location where mesothelioma cancer occurs also known as pleural mesothelioma. Peritoneum, the protective covering that lines the abdominal cavity may also develop malignant tumors and cause peritoneal mesothelioma.

Mesothelioma is one of the rarest cancers in the world that is caused only by exposure to asbestos. Its exposure can be direct, by inhalation of asbestos or indirect exposure in which the asbestos particles are inhaled from the clothing, hair, equipment or other articles that were previously exposed to asbestos.

Causes of Mesothelioma

Asbestos is a naturally occurring fibrous mineral that is mined in different parts of the world due to its wide utility in various industries. However, it is a deadly carcinogen too and a mojor cause of mesothelioma and asbestosis.

Asbestos fibers are known to cause cancer of the mesothelium. Asbestos is the fibrous form of several minerals and hydrous silicates of magnesium found under ground. There are 3 types of asbestos, the blue one, the while one and the brown one. Of all these 3 types, the blue one also called amphibole, long and thin in structure is more carcinogenic than white or chrysolite asbestos or the brown one known as amosite.

However, in some cases the brown asbestos has also been found to cause mesothelioma. And it is for this reason that people exposed to asbestos even for a short period are vulnerable to the disease.

Pleural Mesothelioma

Asbestos fibers are very fine and easily make their way to the lungs where they settle down in the parenchyma of the lung and penetrate the pleura that later develops malignant mesothelial plaques.

Pleura, which anchors lungs to the chest cavity, is itself a double-layered membrane. The inner layer called visceral pleura surrounds the lungs, while the outer one, known as parietal pleura, forms the lining of the pleural or chest cavity. The two pleural layers are filled with a fluid that helps them to slide over each other as we breathe. As the disease progresses, the delicate pleural membranes thicken and press the lungs. A fluid secreted by the malignant cells, pleural effusion, may also collect between visceral and parietal pleurae that causes problem in breathing and other complications.

Peritoneum Mesothelioma

The asbestos fibers may also cause cancer in the peritoneum, known as peritoneal mesothelioma. This leads to thickening of the membranes surrounding abdominal organs and collection of a fluid, ascites in the abdominal cavity making it swell.

Though it is yet not clear how peritoneal mesothelioma develops, it is believed that from lungs, the asbestos fibers are transported to abdomen and its organs by the lymphatic system or they may be deposited in the gut through saliva contaminated by the asbestos fibers.

Pericardial Mesothelioma

This is the rarest type of mesothelioma cancer that comprises of only 5% of all the mesothelioma cases. Like other types of mesothelioma cancer, pericardial mesothelioma is also caused by the inhalation of asbestos dust and fibers. The lining of the chest cavity which protects the heart is known as pericardium. It is provided with a natural fluid or mucous that provide continuous lubrication to the heart so that it can work properly and perform its functions.

It is a very deadly disease that destroys the tissues around the heart and diminishes the survival chances of the patient. As the asbestos particles settle further into the lining of the chest or pericardial, the cancer spreads in the body. It destroys the heart tissues and muscles that is very hazardous to life and proves fatal for the patient.



Judith

Jennifer White asked:


Mesothelioma is a deadly form of cancer that affects the serous membranes surrounding the major organs of the body i.e. the lungs, heart and the abdominal organs, causing these vital organs to inflate with excessive fluid. This fluid further causes the improper functioning of the organs. The only known cause of this cancerous tumor is asbestos exposure. In this disease, malignant cells are built up in the protective linings (serous membranes) of several internal organs known as mesothelium. Different organs in the abdomen cavity can get affected by mesothelioma because of the presence of the protective linings surrounding them. The most common types of mesothelioma include:

* Pleural Mesothelioma,

* Peritoneal Mesothelioma, and

* Pericardial Mesothelioma.

Pleural Mesothelioma:

Pleural Mesothelioma is a tumor in which the lining of the lungs, or lung pleura, gets affected by malignant cells. The pleura is a soft protective tissue that surrounds the lungs in the chest cavity. It helps the lungs in breathing (respiration) by producing a serous fluid that lubricates the pleural surfaces to avoid the teasing of the lungs against the chest wall. The malignant cells, once entered the pleura, begin to spread and affect the surrounding organs and tissues. This leads to further complications resulting pain and severe symptoms.

Mesothelioma affecting pleura is of two categories:

Diffused or Malignant (Cancerous):

It is the serious form of pleural mesothelioma that affects the pleural lining of the lungs and its surrounding organs.

Localized and Benign (Non-cancerous):

It is the non-cancerous form of mesothelioma, which does not affect all parts of the body except the pleura. However, it constricts the lung causing shortness of breath, and in some severe cases, pneumothorax (lung failure).

Peritoneal Mesothelioma:

Peritoneal Mesothelioma is a tumor of the peritoneum membrane or the abdomen lining, affecting many organs in the abdominal cavity including stomach. This form of mesothelioma cancer is less common than the pleural form but is more aggressive, resulting severe symptoms and short life expectancy. Like many other cancers, peritoneal mesothelioma can also be either malignant or benign.

Pericardial Mesothelioma:

Pericardial or Pericardium Mesothelioma is the rarest form of cancer, counting less than 10% of mesothelioma cases. In this form of cancer, fluid gets accumulated in the sac that encloses the heart. The main cause of this disease is the inhalation of asbestos fibers.

Due to the rarity of this disease, doctors and researchers have not clearly understood how the asbestos fibers enter the heart lining or pericardium. The only logical explanation so far about this form of cancer is the possibility of the asbestos fibers, converted into tiny pieces, transported from the lung into the heart by means of blood circulation. Once the asbestos fibers enter the heart, they expand the tissues in the chest cavity and the pericardium with excessive liquid, disrupting the working of the heart and causing chest pains with breathing disorders.

Each year, approximately 2,000 new cases of mesothelioma are diagnosed. At some point of their lives, the patients of mesothelioma have been exposed to asbestos that later cause the hideous cancer of mesothelioma. If you, at some point of your life, have worked in an asbestos-rich environment or used any asbestos materials, you should contact a mesothelioma doctor for correct diagnosis and best treatment options available.



Joe